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PET Mexico Progress Update
Anastasios Tsakaridis,
 James Anderson
&
Angel Cardenas

What is PET Mexico S.A. de. C.V. ?
PET Mexico is a Mexican Corporation.
PET Mexico will Construct Cyclotron Facility in Guadalajara, Mexico.
Will Produce and Distribute Radioisotopes for PET and other Imaging services.
Initial facility will produce up to 400 doses per day.

Timetable for Cyclotron Development
0 Days – 90 Days-
Procure Permits from Nuclear Regulatory Commission
Purchase Property for Cyclotron Facility
Finalize design of Cyclotron facility
Procure Building Permits.

Timetable for Cyclotron Development
90 Days- 270 Days-
Construction of Cyclotron Facility.
Fabricate, Install and Test Cyclotron and Pharmaceutical equipment.
Training of Personnel for Facility.
Coordinate Development of PET scanning facilities with Cyclotron facility.

Timetable for Cyclotron Development
270 Days- 300 Days-
Finish Training of Personnel.
Complete Cyclotron Facility and Offices.
Procure Occupancy permits.
Finalize Delivery Agreements with PET Facilities.

Timetable for Cyclotron Development
Day 301-
Begin operations.

Timetable for Cyclotron Development
Projected Funding completion
-November 1st 2003
Projected Cyclotron Facility completion          - September 1st 2004

Meeting the Needs

Key Personnel & Advisors
Anastasios Tsakaridis
Angel Cardenas
James Anderson
John Zehner
Dr. Daniel Espinosa-Blake
Dr. Ramirez Aldrete
Dr. Luis Vargas-Rodriguez
Licenciado Filiberto Maldonado Mercado
Dr. Rafael Martinez Heredero

Our Strengths

Cyclotron 18/9

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Brain Tumor- Differentiate Recurrent tumor from Radiation necrosis.
Differentiate Primary CNS Lymphoma from Toxoplasmosis
Exclude Metastatic disease to Brain

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Breast Cancer Identify involved Auxiliary Nodes or distant Metastatic Disease
Exclude Local Recurrence of Disease
Evaluate response to treatment.

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Colorectal Cancer Identify involved Auxiliary Nodes or distant Metastatic Disease
Exclude Local Recurrence of Disease
Evaluate response to treatment.

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Head & Neck Cancer Determine extent of Local, Regional and Distant Disease
Detect Recurrent/ Residual tumor following definitive therapy

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Lung Cancer Distinguish Malignant from Benign Pulmonary Nodules Stage for mediastinal or distant metastatic disease
Use in Radiotherapy treatment planning
Detect Recurrent/ Residual tumor following definitive therapy

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Lymphoma Determine extent of disease and measure treatment response

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Musculo-skeletal Evaluate local extent of Tumors disease and exclude distant metastasis
Measure Treatment response and exclude recurrent/residual tumor following definitive therapy

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Melanoma Identify extent of local and regional disease spread in patients with high risk melanoma  (primary tumor > 4 mm) or in suspected recurrence.

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Ovarian Cancer Detect Recurrent/Residual tumor prior to surgical exploration or additional therapy

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Pancreatic Cancer Differentiation of benign
processes such as Pancreatitis, Mucinous Cyst Adenoma and Pseudocyst from malignant processes.

Clinical Applications of PET Imaging
Oncology
Diagnosis Application
Thyroid Cancer Detect metastatic or locally recurrent disease in patients with elevated thyroglobulin after definitive initial treatment and negative 1-131 examination.

Clinical Applications of PET Imaging
Neurology
Diagnosis Application
Dementia Differentiate Alzheimer’s Disease from Multi-Infarct Dementia

Clinical Applications of PET Imaging
Neurology
Diagnosis Application
Epilepsy Local seizure focus in patients with intractable complex seizure disorders

Clinical Applications of PET Imaging
Neurology
Diagnosis Application
Stroke Evaluate extent of disease and recovery following therapy

Clinical Applications of PET Imaging
Cardiology
Diagnosis Application
Myocardial Viability Distinguish viable myocardium from infarcted tissue in patients with suspected hibernating or stunned myocardium

Clinical Applications of PET Imaging
Cardiology
Diagnosis Application
Coronary Artery Identify Ischemic disease
Disease

Clinical Applications of PET Imaging
Cardiology
Diagnosis Application
Preoperative Prognostic Evaluate extent of disease in Assessment patients being considered for interventional re-vascularization or transplantation.

Next Steps
Complete Project Financing
PET Mexico Imaging Center Consulting.
Periodic Updates for Physicians and Clinics.